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Main Medications
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Diabetes
Step Therapy Drugs (basic tier 1 medications)
Actos (pioglitazone)
Metformin/Metformin ER (some brand names below)
- Gluchophage
- Glumetza
- Riomet
Sulfonylurea
- Amaryl (glimepiride)
- Glucotrol (glipizide)
- Glynase/Diabeta (glibenclamide)
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Basal Insulins (long-acting)
Basaglar (insulin glargine)
- pen (100 units/mL)
Humulin N (NPH)
- vial (100 units/mL)
- pen (100 units/mL)
Insulin Glargine-yfgn (unbranded)
- vial (100 units/mL)
- pen (100 units/mL)
Lantus (insulin glargine)
- vial (100 units/mL)
- pen (100 units/mL)
Levemir (insulin detemir)
- vial (100 units/mL)
- pen (100 units/mL)
Novolin N (NPH)
- vial (100 units/mL)
- pen (100 units/mL)
Semglee (insulin glargine-yfgn)
- vial (100 units/mL)
- pen (100 units/mL)
Soliqua (insulin glargine-lixisenatide)
- pen (100-33 units-mcg/mL)
- this is a mixed GLP-1 & long-acting
Toujeo (insulin glargine)
- pen (300 units/mL)
Tresiba (insulin degludec)
- vial (100 units/mL)
- pen (100 units/mL)
- pen (200 units/mL)
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Bolus Insulins (short-acting/meal-time)
Admelog (insulin lispro)
- vial (100 units/mL)
- pen (100 units/mL)
Afrezza (regular insulin)
- it's complicated; rare medication
Apidra (insulin glulisine)
- vial (100 units/mL)
- pen (100 units/mL)
Fiasp (insulin aspart)
- vial (100 units/mL)
- pen (100 units/mL)
Humalog (insulin lispro)
- vial (100 units/mL)
- pen (100 units/mL)
- pen (200 units/mL)
Humulin R (regular insulin)
- vial (100 units/mL)
- pen (100 units/mL)
- vial (500 units/mL)
- pen (500 units/mL)
Insulin Lispro (generic)
- vial (100 units/mL)
- pen (100 units/mL)
Insulin Aspart (generic)
- vial (100 units/mL)
- pen (100 units/mL)
Lyumjev (insulin lispro)
- vial (100 units/mL)
- pen (100 units/mL)
- pen (200 units/mL)
Novolin R (regular insulin)
- vial (100 units/mL)
- pen (100 units/mL)
Novolog (insulin aspart)
- vial (100 units/mL)
- pen (100 units/mL)
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Insulins (hybrid)
Humalog 50/50 pen or vial
Humolog 75/25 pen or vial
Humulin 70/30 pen or vial
Novolin 70/30 pen or vial
Novolog 70/30 pen or vial
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SGLT-2 Inhibitors (cardiovascular & renal protection)
Invokana (canagliflozin)
- 100 mg tablets
- 300 mg tablets
Jardiance (empagliflozin)
- 10 mg tablets
- 25 mg tablets
Farxiga (dapagliflozin)
- 5 mg tablets
- 10 mg tablets
Steglatro (ertugliflozin)
- 5 mg tablets
- 15 mg tablets
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GLP-1 Agonists (GI issues & weight loss)
Byetta (exenatide) - twice daily
- 5 mcg/0.02 mL pen
- 10 mcg/0.04 mL pen
Bydureon (exenatide) - discontinued
Bydureon BCise (exenatide) - weekly
- 2 mg/0.85 mL auto-injector
Trulicity (dulaglutide) - weekly
- 0.75 mg/0.5 mL auto-injector
- 1.5 mg/0.5 mL auto-injector
- 3 mg/0.5 mL auto-injector
- 4.5 mg/mL auto-injector
Victoza (liraglutide) - daily
- 18 mg/3 mL pen (0.6 mg, 1.2 mg, & 1.8 mg doses)
Ozempic (semaglutide) - weekly
- 2 mg/1.5 mL pen (0.25 mg or 0.5 mg dose)
- 4 mg/3 mL pen (1 mg dose)
- 8 mg/3 mL pen (2 mg dose)
Adlyxin (lixisenatide) - daily
- 10 mcg/0.2 mL pen
- 20 mcg/0.2 mL pen
Rybelsus (semaglutide) - daily
- 3 mg tablet
- 7 mg tablet
- 14 mg tablet
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DPP-4 Inhibitors (cannot be taken w/ GLP-1)
Januvia (sitagliptin)
Onglyza (saxagliptin)
Tradjenta (linagliptin)
Nesina (alogliptin)
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DPP-4 Inhibitors (mixed)
Janumet (sitagliptin & metformin)
Janumet XR (sitagliptin & metformin ER)
Kombiglyze XR (saxaglitpin & metformin ER)
Glyxambi (linagliptin & empagliflozin)
Jentadueto (linagliptin &metformin)
Kazano (alogliptin & metformin)
Oseni (alogliptin & pioglitazone)
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Hyperlipidemia/Hypercholesterolemia
Statins (often cause myalgia/muscle pain)
Altoprev (lovastatin)
Crestor (rosuvastatin)
Lescol XL (fluvastatin)
Lipitor (atorvastatin)
Livalo (pitavastatin)
Pravachol (pravastatin)
Zocor (simvastatin)
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Expensive Alternatives (generally for ASCVD patients)
Nexletol (bempedoic acid)
- tablet
Nexlizet (bempedoic acid & ezetimibe)
- Nexletol & Jardiance
- tablet
Repatha (evolocumab)
- PCSK-9 inhibitor
- Rx & PA SureClick 140 mg Q 2 weeks
- injectable
Praluent (alirocumab)
- PCSK-9 inhibitor
- 75 or 150 mg Q 2 weeks (provider's choice)
- injectable
NOTE: most common ASCVD we see is CAD
ASCVD = atherosclerotic cardiovascular disease
CAD = coronary artery disease
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Hypertriglyceridemia
Medications (oral)
Lovaza (omega 3 ethyl esters)
Omega-3 Polyunsaturated Fatty Acids
Tricor (fenofibrate)
Vascepa (icosapent ethyl capsules)
- Take 2 tablets by oral route BID (360 per 90 days)
- We always Rx the 1 gram tablets
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Thyroid Medications
Medications (oral)
Armour Thyroid (thyroid desiccated)
Cytomel (liothyronine)
Euthyrox (levothyroxine)
Levo-T (levothyroxine)
Levoxyl (levothyroxine)
NP Throid (thyroid desiccated)
Synthroid (levothyroxine)
- can use Synthroid Delivers for $75/90 days
Tirosint (levothyroxine capsules)
- capsules generally work better for malabsorption.
- can use Tirosint Direct for $150/90 days
Unithroid (levothyroxine)
WP Thyroid (thyroid desiccated)
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Levothyroxine = LT4
Liothyronine = LT3
Thyroid Desiccated = LT3 & LT4
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Osteoporosis
Bisphosphonates
​Actonel (risendronate)
- oral only
- daily, weekly, monthly, or 2 days in a row monthly
Boniva (ibandronate)
- oral once monthly
- IV once every 3 months
Fosamax (alendronate)
- oral only
- daily or weekly
Reclast (zoledronic acid)
- IV only
- once yearly in medical office/outpatient
- Jenn handles these, generally goes to NWR
- CPT code: J3489
- Administration CPT codes: 96365 or 96366
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PTH Analogs
Forteo (teriparatide)
- 7.44 mL per 90 days (3 pens)
- inject 20 mcg by subq route once daily
- generic available: Teriparatide
Tymlos (abaloparatide)
- 4.68 mL per 90 days (3 pens)
- inject 80 mcg by subq route once daily
- cheaper than Forteo & generic Teriparatide
- only approved for women, FDA reviewing for men
*Therapy limited to 24 months total between both meds; PA for 24 months as duration of therapy for either (Tymlos is 18-24 months, Forteo is 24 months)
*Be sure to Rx pen needles (BD nano) w/ these meds
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Other
Prolia (denosumab)
- inject 60 mg every 6 months (120 mg per year)
- administered in medical office/outpatient
- Holli handles these, generally goes to NWR
- CPT code: J0897
Evenity (romosozumab)
- inject 210 mg every month (2x 105 mg injections)
- therapy duration limited to 12 months
- administered in medical office/outpatient
- Holli handles these, generally goes to NWR
- CPT code: J3590
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Hypogonadism
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Medications (topical)
Androderm (patches)
Androgel 1% Gel (pump/packets)
Androgel 1.62% Gel (pump/packets)
Testosterone Cypionate (intramuscular injection)
- AKA depo testosterone
- 200 mg/mL, 10 mL vials or 1 mL vials
- inject 1 mL by IM route once every 14 days (this is just standard, sometimes it does vary)
Foresta (pump)
Testim (packets)
- testosterone 50 mg/5 gram (1%) - this is generic
*Testosterone comes in pumps, packets, patches, and injections. Pumps, packets, and patches are topical (on skin). There is a generic testosterone for all (or close to) testosterone products.
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Growth Hormone Disorder
Acromegaly Specialty Meds (injectable)
Sandostatin
Somatuline Depot
Somavert
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Acromegaly Meds (oral)
Mycapssa
Cabergoline
Bromocriptine
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Growth Hormone Deficiencies (injectable)
Genotropin
Humatrope
Norditropin
Nutropin/Nutropin AQ
Omnitrope